An anti-anxiety agent, such as diazepam is appropriate to prescribe if the patient suffers from severe anxiety or agitation. An anti-psychotic medication, such as thioridazine or haloperidol, may be prescribed if a patient decompensates into severe agitation or delusionsal thinking which may result in self-harm or harm to others.
Although the patient's functioning may be improved, the paranoid symptoms often remain intact. Some studies indicate that symptoms improve following drug treatment, but the same results sometimes occur among patients who receive a placebo, a "sugar pill" without active ingredients. This finding suggests that in some cases the paranoia diminishes for psychological reasons rather than because of the drug's action.