Well Davidez that is a very general question. What is the purpose of your trip? How much money do you have? How old are you.. ?
The reason I'm asking all this is because Panama is a very diversed place. In general, I would recommend the Islands "Las Bocas" or "Boca Del Torro" which are located in the north. It's a beutiful group of islands where you can go and "chill", have drinks on the beach, etc. The lodgings are not so expensive and it is beutiful there. Highly recommended..