Amniotic fluid from pregnant cows is used in facial and body moisturisers due to its neutral PH of 7. Yes it is safe. But does it work? Of course it does, growing up on a farm i never once saw a cow with wrinkles.
On the other hand does hydroderm work. Personally i don't know but here is a partial review of the product with the link following.
Thinking of buying Hydroderm? Don’t. There are so many complaints against this product that to nominate it as one of the best anti-aging skin care products is out of the question. Facts show that out of 30 users who tried this anti-wrinkle cream product, only 37% of them recommended this. It simply shows that the satisfaction level of most users who tested Hydroderm is way below the norm. If you still think it is the best wrinkle cream product in the world, try it out but don’t say we didn’t warn you.
http://www.bestantiwrinklecreamreviews.com/hydroderm-review.php