Two different drugs two different Doctors. Statin drugs, started pain when trying to sleep in stomach, strange feeling in right temple,arms never pain when going to sleep (couldn't sleep), when walking became weak in legs, when mucles twitch happen in chest muscle I quit. felt better right away. Metformin took with food twice a day 500mg. Week one and two ok. After that I was leaving house and felt crap running down leg no other feeling. Decided if out with others better not take it. Became where I just not wanting to eat. Went to bed woke with the worst vomting and diarrhea all night. Un-like with the flu where you feel better after you vomit I didn't. Can't tell what a mess it was. I couldn't eat or drink for a day second after still couldn't eat. Quit Metformin when I got sick. Couldn't hold it down any way. E-mailed my Dr. told her what I went thru. E-mailed back if glucose doesn't go down will add another pill. No thanks took up walking, it helped. I will never take it again. Medicine works for some, does nothing for some, and does harm to others. They can test DNA to see how it will work before hand. But it cost money. My Dr. Did not care, You ask straight questons about it. And get to nothing back. They are treating symtoms not what the cause is. No money in that.