first president without vice president
George clinton died while in office. Under Thomas Jefferson.
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James Madison started his term with George Clinton who was with him 1809-1812. From 1812-1813 he served without a VP. Elbridge Gerry became his VP in 1813. Then 1814-1817 he served without a VP.
When John Tyler took the place of William H. Harrison in 1841 he took office without a VP.
You can get more information here http://www.presidentsusa.net/
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