Taking methadone improperly will increase your risk of serious side effects or death. Even if you have used other narcotic medications, you may still have serious side effects from methadone. Follow all dosing instructions carefully.
Like other narcotic medicines, methadone can slow your breathing, even long after the pain-relieving effects of the medication wear off. Death may occur if breathing becomes too weak. Never use more methadone than your doctor has prescribed. Call your doctor if you think the medicine is not working.
Do not stop using methadone suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Do not drink alcohol while you are taking methadone. Dangerous side effects or death can occur when alcohol is combined with methadone. Check your food and medicine labels to be sure these products do not contain alcohol. Methadone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Before taking methadone, talk to your doctor if you have:
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a personal or family history of "Long QT syndrome"; -
asthma, COPD, sleep apnea, or other breathing disorders; - liver or kidney disease;
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underactive thyroid; -
curvature of the spine; -
a history of head injury or brain tumor; -
epilepsy or other seizure disorder; -
low blood pressure; -
gallbladder disease; -
Addison's disease or other adrenal gland disorders; -
enlarged prostate, urination problems; -
mental illness; or -
a history of drug or alcohol addiction.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:
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shallow breathing; -
hallucinations or confusion; or -
fast or pounding heartbeats, chest pain, trouble breathing, feeling light-headed, fainting.
Other, less serious side effects may be more likely to occur, such as:
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feeling anxious, nervous, or restless; -
sleep problems (insomnia); -
dizziness, drowsiness, or weakness; -
dry mouth, nausea, vomiting, diarrhea, constipation, loss of appetite; or -
decreased sex drive, impotence, or difficulty having an orgasm.
This list is not complete and other side effects may occur. Tell your doctor about any unusual or bothersome side effect.
Good luck and best wishes.