Responding to your question and also the answers above, it is DEFINITELY more dangerous for a horse to have twins than a human. Humans are smaller and need less developmental space and nutrition than a horse. Usually the smaller the animal the better chance it will have of having a healthy set of multiple babies.
There are many recorded incidences of both twins dying at birth or even being stillborn. If both are born one will be considerably smaller and it almost always dies. Even if it survives it could still have complications later on in life. The larger of the two will also probably be smaller than normal. There is even a higher chance of the mare dying in labor with twins than with only one foal.
Even if both twins survive and are healthy a mare's body is only equipped to support one foal at a time. They will be competing for milk and will probably need extra nutritional support from a human caretaker.
The safest route is to abort one foal so you'll have a considerably better chance of survival for both the other foal and the mare.