yeah man theres definately an effect when you take xanax and then drink,even if you tkae them hours before you drink you still get sloppy drunk and it makes you fearless,it changes who you are,ive done it,so fis hand experience...if you do it you wont emember ANYHING from the nigh before,maybe jus like quick flashes but thats it. i dunno... i hope that answered ur question... i dunno, i seen it so i decided to tell you....later :)