Aside from knowing how to run a business you will need a great deal of self-discipline so as not to be distracted. Remember that in a remote office you are not that accessible for questions, comments, etc. Therefore set up a room that you can lock from the inside and seclude yourself from all sorts of interferences. Make sure the room is well lit, air conditioned and heated, has all the facilities of an office, comfortable chairs and desks, sufficient electrical outlets for computers, printer, fax, etc.