Well, I was born in Orlando, so my answer might be a bit biased. ;-)
Orlando has SO much to offer outside of Disney.
How you spend your vacation though depends on what you want to get out of it.
If all you want to be while you're down there is a tourist blowing away your hard earned cash to Mickey and Goofy, then look no further than Lake Buena Vista.
However, you could have a great adventure and save some money by staying outside of Disney and checking out everything else there is to see and do.
Hint, avoide I-Drive (International Drive). Tourist trap. Overpriced crap, and gas would be on average of 50¢ more per gallon than elsewhere.
Also, avoid South Orange Blossom Trail (OBT/ SR 441). Too many bad areas if you don't know where you're going.
Check out The Orlando Science Center, the Orlando History Museum, Leu Gardens, Kennedy Space Center.
Spend a day at the beach! Coccoa Beach is only about an hours drive from Orlando east on SR 528 (Bee Line Expressway).
Check out Silver Springs (an hour north of Orlando in Ocala up the Turnpike) for crystal blue water and river rafting. Famous for its glass-bottom boats.
You can check out live manatees in Crystal River (about 2 hours NW of Orlando).
Sea World believe it or not is a blast! So is Wet N' Wild water park.
Think about how you really want to spend your vacation. Do you want to be running around being herded like cattle from one ride to the next while a megacorporation steals your money, or do you actually want to relax?