I'm 57 years old and was diagnosed with high blood pressure at 17. So, I've been taking meds for this most of my life. About 15 years ago my doctor found a study on the time of day when most people have heart attacks and/or strokes. Because the results of this study showed that the early morning hours appeared to be the most critical time, (because during this time some people become startled when waking from alarms or bad dreams) my doctor suggested that I take my meds at night before going to sleep. The doctor who told me this has since retired and when I had to see a new doctor I explained this to her and she agreed with the 1st doctor.