The "old testament" - the five books of Moses, the Prophets, and the Scriptures - are almost entirely in Hebrew, except for portions of the book of Daniel, which is in Aramaic, a language related to Hebrew. The "new testament" manuscripts were written in Koine Greek.
I've heard suppositions that some of the new testament was translated from Hebrew; my Greek isn't good enough to be able to tell. I never heard about it having been translated from Aramaic, as colfax said; I'd be interested in knowing more about that.
