Do not take duloxetine together with thioridazine (Mellaril), or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate). You must wait at least 14 days after stopping an MAOI before you can take duloxetine. After you stop taking duloxetine, you must wait at least 5 days before you start taking an MAOI.
You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Avoid drinking alcohol while taking duloxetine. Alcohol may increase the risk of damage to your liver.
Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by duloxetine. Tell your doctor if you regularly use any of these other medicines.
Duloxetine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
This is the best info on the drug and its generic name. As with all medication, especially anti-depressant such as this, and SSRI, a SELECTIVE SERATONIN REUPTAKE INHIBITOR (the classification of this medication) should be monitored by a Psychiatrist and any ill effects should be reported to him/her immediately. Usually these meds take about a month to get into your system to make you feel better. So some side effects like sleepiness may subside with time when you first start taking it. ALL medications cause different responses in different people, just take as directed and seek help if you feel suicidal or your depression worsens.
Good luck. I hope you feel better real soon!
Katie
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