If you're planning to spend time in Amsterdam, a very cool place to go, which will give you some understanding of the various cultures around the globe that Holland has had interaction with during its colonial past, is the Tropenmuseum - has very innovative, atmospheric, walk-through installations which immerse you in the sounds and sights of these cultures, plus the museum cafe is a good place to get an idea of the various ethnic cuisines with with Amsterdam abounds.
the "De Pijp" area is also very nice, not so touristy, lots of funky bars, cafes, shops, etc - good lively street market, and a nice park there too.
the area round the Vondelpark is different again, very classy, elegant art Nouveau-y/late 19th cent buildings and the park again is wonderful. Also a bit off the main tourist drag.